The Colorado Rockies (24-36) lost their sixth in a row, and fell to 0-7 this season in interleague games after an 8-5 loss to the visiting Oakland Athletics (27-35) last night. Rockies pitchers now have the worst ERA (6.27) in Major League Baseball. The second contest of the three-game series is tonight at 6:40 at Coors Field (TV: Root Sports).

Colorado starter Jeremy Guthrie (3-5) was handed a 4-0 lead after the first inning, but unraveled in the third. On an 0-2 count, Guthrie hit Jemile Weeks, who later advanced to third base on a wild pitch, then walked Josh Reddick. Seth Smith and Brandon Inge followed with back-to-back doubles before Brandon Moss crushed a hanging curveball that ended up in the third deck and gave the A’s a 5-4 lead.

A solo shot off the bat of Cliff Pennington one out later made it 6-4 and invited a chorus of boos from the 33,635 in attendance.

It was Guthrie’s fifth straight start in which he allowed at least five runs, made more frustrating considering Oakland ranks last in the Majors in batting average and slugging, second-to-last in on-base percentage and third-worst in runs scored.

“When I struggled in the past, I lost a lot of confidence,” Guthrie said. “Right now, I believe I can get people out. It just hasn’t happened.”

A bright spot in the midst of Colorado’s slide has been the play of Tyler Colvin. In the last three games, Colvin is hitting .700 with a double, four homers — including a leadoff blast Tuesday — six RBIs and five runs scored. Colvin also received a standing ovation when he robbed Pennington of a home run in the eighth inning.

Todd Helton knocked his sixth home run, a solo shot off Colon in the bottom of the fifth.

The Rockies have played well defensively and are still putting up substantial numbers, scoring at least five runs in each of their last three losses. But those losses are starting to take their toll.

Tickets are available for tonight’s game at Coors Field vs. the Oakland Athletics, and can be purchased by calling (800) 388-ROCK, or click here.