uPDATE: The crash has been cleared and I-80 is open both directions.

Original story:

I-80 eastbound between Cheyenne and Laramie is closed due to a crash.

The Wyoming Highway Patrol says it is unknown at this time when the road will be opened. The WHP says commercial traffic is being sent back to Laramie and those vehicles have the option to use HWY 287. Passenger vehicles are being rerouted onto Wyoming Highway 210, or Happy Jack Road, to Cheyenne. The Wyoming Road and Travel report can be viewed here. 

The WHP says the crash involved one commercial vehicle and one passenger vehicle and occurred at milepost 336 on the eastbound lane of I-80, between the Vedauwoo interchange and Remount Road interchange.

We will update this post as more information becomes available.